Pathology
Dr. Sathyavathi R. Alva
MBBS – Kasturba Medical College, Mangalore
MD (Pathology) – Kasturba Medical College, Mangalore
General Information
Pathology, in its broadest sense, is a scientific discipline focused on the investigation of the causes and effects of diseases or injuries. It is derived from the Greek words ‘pathos’ meaning ‘disease’ and ‘logia’ meaning ‘study of’, hence it literally translates to ‘the study of diseases’. It encompasses a wide array of bioscience research fields and diverse medical practices. However, in the realm of contemporary medical treatment, the term ‘pathology’ is typically applied in a more specific manner to denote processes and diagnostic tests that fall within the purview of what is known as ‘general pathology’.
General pathology is an extensive area of medicine that involves several distinct yet interconnected medical specialties, all of which are dedicated to diagnosing diseases. These diagnoses are typically conducted through the detailed examination and analysis of tissue samples, cell specimens, and body fluids. Pathologists, the medical practitioners specializing in this field, utilize this information to draw conclusions about a patient’s health status, guiding further treatment approaches.
At a more detailed level, pathology dives into the complex world of disease processes, studying changes in body tissues and organs that lead to or are caused by disease. This includes gross pathology, where the disease’s characteristics are visible to the naked eye, and histopathology, which involves microscopic examination of tissue to observe disease at a cellular level.
Furthermore, pathology explores the molecular mechanisms underlying disease states, a field known as molecular pathology, which is increasingly becoming important with the rise of precision medicine and personalized treatments. Here, pathologists investigate genes, proteins, and other molecules to understand how diseases develop, progress, and how they might be treated or prevented at the molecular level.
Clinical pathology, another crucial branch, is concerned with laboratory testing and analysis of bodily fluids such as blood and urine, and tissue samples for diagnosis, prognosis, and monitoring treatment response. This field is further divided into specialties like clinical chemistry, hematology, microbiology, immunology, and transfusion medicine, each focusing on different aspects of disease diagnosis and management.
In essence, the field of pathology is integral to understanding the ‘why’ and ‘how’ of disease. It provides the fundamental basis for medical decision-making by offering definitive diagnoses, providing insights into disease progression, and informing the selection of the best treatment options. As medical science continues to advance, the role of pathology in understanding and combatting disease will undoubtedly continue to grow and evolve.